Understanding HER2 HER2 proteins occur on the surface of breast cells, whether cancerous or normal. A gene we all have (HER2 or ERBB2) carries the instructions or blueprint for manufacturing these proteins. Each cell contains two copies of the gene. When there are extra copies of this gene (HER2 amplification) the result is an increased number of HER2 receptors on the surface of breast cells (HER2 overexpression). While normal breast cells have these receptors, HER2-positive breast cancer cells have up to 100 times as many....

Although Europe is faring better, McKinsey says that nearly 60 million jobs are at risk across Europe and the United Kingdom. There are also warnings of a potential “jobs bloodbath” across Africa. There’s no doubt that some types of businesses have no choice but to let many employees go. But others are rushing to take such steps. Case in point: Houston billionaire Tilman Fertitta, owner of the Houston Rockets and a $4....

In a joint statement shared on Twitter, the couple said, “After a great deal of thought and a lot of work on our relationship, we have made the decision to end our marriage.” They said they will continue to work together at the foundation they co-founded and co-chair, but “no longer believe [they] can grow together as a couple in this next phase of [their] lives.” The Bill and Melinda Gates Foundation has more than $51 billion in assets, according to CNBC and Bill, the co-founder of Microsoft, is worth about $130 billion, according to Forbes....

Police officers and firefighters have been searching for survivors amid the debris, as at least 140 buildings have been damaged by the disaster. During a press conference, Tennessee Governor Bill Lee mentioned that a large number of people are either missing, injured or have been admitted to nearby hospitals, according to Fox News. Lee described the severity of the ordeal, saying, “We have had loss of life all across the state....

There’s no distance this time—just the possibility of stir-crazy drama and much-invited updates on their relationships, for fans who want to know which couples are still together. The series won’t be an extended run. It will air five episodes, all which will feature different cast members from seasons past. Some of the couples featured might come as a surprise, while others are exactly who fans would expect to show up....

During his remarks Thursday, Trump, who has derided the impeachment process against him as a “witch hunt,” focused on his success as president, Democratic policies he disagreed with and what he said were unfair attacks against him. He didn’t apologize for his behavior, as Clinton did in 1999, instead saying, “I did nothing wrong.” “We’ve been going through this now for over three years,” Trump said. “It was evil, it was corrupt, it was dirty cops, it was leakers and liars and this should never ever happen to another president ever....

“We are experiencing fires the likes of which we haven’t seen in many, many years,” Governor Gavin Newsom said at a news conference Wednesday. “That is a resource challenge where they are stretched in ways where we haven’t seen in the last few years.” These devastating wildfires can make anyone feel powerless. However, there are several ways to help those affected by this natural disaster. Make a donation to American Red Cross....

After the show’s 18th season (and third for ABC) saw major changes made to its format, to adopt a remote style due to COVID-19, the show will continue using a virtual setup for its 2021 edition. Hopeful stars between the ages 15 and 28 will have the opportunity to participate in the “Idol Across America” auditions in every state, beginning on Monday, August 10. Most of the audition dates cover three states per day; the process is set to conclude on September 9....

Yes, that Aaron Rodgers, as in the star quarterback of the Green Bay Packers. Some viewers may have been left scratching their heads at the Rodgers mention, but for anyone who’s been closely following the football star as of late, it shouldn’t have come as a surprise. The Rodgers and Foster connection goes back to at least his NFL MVP speech on February 6. While speaking that night, Rodgers surprised many when he thanked his fiancé, but didn’t reveal her identity....

The Mexico international has scored five goals in 18 Premier League appearances this season but has started only once in the top flight since David Moyes took charge in November. The Hammers are reportedly prepared to listen to offers for the 29-year-old this month and his representative, Eduardo Hernandez, says a number of clubs have already expressed their interest. “There are several clubs interested in his services. He’s a player everyone knows,” he told Fox Sports....

The girl was at the Honey Ladies stand when the gunman, since named as 19-year-old Santino William Legan, approached and opened fire, striking the parents of the three-year-old boy with her, who own the business. Candice Marquez, the girl’s great aunt, was working at the stand with her sister, Cheryl Low. They had gone to the toilet before the shooting started at the festival in California on Sunday. “She was brave....

The other is Claudio Ubeda, the beleaguered Argentina coach who against all odds saw the country’s South American Championship campaign veer from utter disaster to squeezing into the final qualification place. Martinez got the Albiceleste there against all hope, almost single-handed; a last-minute equaliser against Brazil on Wednesday was followed by two goals to sink Venezuela in the final, decisive fixture, with the Selecao’s tepid goalless draw against already eliminated Colombia ensuring Ubeda’s men would sneak into the tournament by a single point alongside Uruguay, Ecuador and Venezuela....

That's a lot of names, when you think about it. And with the average fantasy owner only owning six or seven starters at a given time, that means there's a bunch of pitchers you're paying zero attention to. When you scan our Probable Starters Grid, it's common to see a recognizable name -- usually someone who's had success in the past -- and think, "Is that guy still good, or ....

Voice recognition, long a staple of science fiction, is rapidly moving into the real world. To be sure, there are still a lot of bugs to work out (one Foncard user recently tried to trick Sprint’s system by asking it to “Call Penguin”; the computer connected him to his office). But it’s already clear that voice technology will ultimately change the way people use machines. The major attraction is ease of use, especially for technophobes intimidated by keyboards, mice and a profusion of icons littering the screen....

The 72-year-old has been appointed as head coach until the end of the season following the sacking of Carlo Ancelotti last Thursday. Heynckes has been away from the dugout since leaving Bayern at the end of the 2012-13 season, during which he steered the club to their first treble of Bundesliga, DFB-Pokal and Champions League wins. But the former Real Madrid boss says he has kept up with developments in the European game and is fully prepared for what lies ahead between now and next May....

Data obtained from the Dallas Heart Study showed that people with PCOS had a higher prevalence of high blood pressure, regardless of race or ethnicity. If not controlled, high blood pressure can damage blood vessels and organs. Complications of high blood pressure include vision problems, kidney damage, heart attack, or stroke. Knowing and reducing your risk factors can help you minimize your risk. Risk Factors There are many risk factors for high blood pressure....

The first quarter of 2021 in the stock market could be best defined by the enormous influx of IPOs and SPACs, with private companies hoping to capitalize on the high stock market growth of the last year by getting in on public shareholder support. The growth in tech stocks has also correlated with a boom in other assets, most notably bitcoin and cryptocurrencies. In a huge sign of faith, Tesla recently announced the purchase of $1....

In their quest for an ever-better Internet, the builders of the information superhighway have created some pretty well-paved access roads. The problem is that those up to no good can travel them too, and, armed with the proper knowledge, they can visit almost anywhere they want–including the average person’s computer. So how high is the risk? NEWSWEEK’s Laura Fording asked Bruce Schneier, a security expert and founder and chief technology officer of Counterpane, an Internet security company, for his impressions....

It is still possible that there will not be another air war against Iraq. But if it happens, the campaign will be longer and more difficult than most Americans seem to expect, administration sources say. Iraqi air defenses–smaller now than they were at the start of the Persian Gulf War in 1991, but better organized–may well shoot down some U.S. planes, killing the crews or making them prisoners to be paraded through the streets in manacles....

Parker, who was diagnosed with kidney cancer in November, also represented active players like Alshon Jeffery, Larry Fitzgerald and Jason Pierre-Paul. MORE: Notable sports deaths of 2016 “The family of Eugene Parker is deeply saddened to report the loss of their beloved husband and father,” Parker’s family said in a statement. “Eugene passed away on March 31, 2016 after a brief and heroic battle with cancer.” Draft prospects Jaylon Smith, Laquon Treadwell and Noah Spence had also signed with Parker, who was a star basketball player at Purdue before pursuing a law degree at Valparaiso....