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Stopping such a big and important study is exceptional, but so were the results: letrozole reduced the risk of recurrence among older women by 43 percent. (Most of the 211,000 women diagnosed with breast cancer in the United States each year are postmenopausal.) Goss and his colleagues in the United States and Europe were testing the drug as a follow-up treatment. The women in the letrozole study had recently completed (after surgery) the standard five-year course of tamoxifen, a powerful and widely used drug that eventually loses its effectiveness as, researchers believe, tumors become resistant to it....

You may not have heard of reflux or some new prescription antacids like Aciphex. But chances are, if you’ve read a magazine or watched TV lately, you’ve seen ads for similar drugs, including Prevacid, Protonix and those “purple pills” (as the ads call them), Prilosec and Nexium. Last year these drugs racked up sales of $10.2 billion, second only to cholesterol-lowering statins. Nearly 75 million prescriptions for these medications were dispensed in 2001....

OSHA representatives have been inundated with reports from hospitals citing a severe lack of personal protective equipment, or PPE, needed to keep health care professionals from being exposed to the novel coronavirus, the report said. One of those complaints came from a nurse at Steward Hillside Rehabilitation Hospital in Warren, Ohio which claimed as many as 35 nurses working with COVID-19 patients in two units were imminent danger of infection....

Speaking on CBS This Morning, he rebuked Biden administration claims that the government doesn’t have a plan for distribution, saying that in the meeting the Trump administration laid out “in minute detail how we would ship the vaccine.” His claims come amid escalating case loads of the virus, as well as promising progress with vaccine approvals both in the U.S. and elsewhere. Total confirmed coronavirus deaths in the U.S. had surpassed 282,300, as of Monday, according to data compiled by Johns Hopkins University....

I previously looked at the inflationary forces at work within healthcare, from labor costs to drug prices. But there are other factors affecting the current healthcare revenue cycle. For example, many patients are delaying care, either due to expenses or lingering concerns over COVID, resulting in a decrease in hospital revenue. This is particularly problematic during a time when health systems have already been under fire for a lack of transparency surrounding their pricing....

The 119-page script, a copy of which NEWSWEEK obtained, is the story of Morgan Fraser, a single mother and rookie cop who must learn to make her way in the notorious 77th Street Division. There she must survive the harassment of rogue macho cops in a clandestine organization called Men Against Women (based on a real group Fuhrman belonged to). Fraser must also deal with two lesbian cops who annoy her....

He plays a couple more songs, trying out the different guitars, sorting out the different reverberations they make. A photographer creeps along the far reaches of the loge. He’s been instructed not to get too close to the stage; the clicks of the camera will distract Springsteen’s obsessive quest for perfection. He plays “Sinaloa Cowboys,” another harsh, strained breath of a song. Midway through the first verse, the guitar emits a honk of feedback....

The 22-year-old forward has been struggling with a muscle injury in recent weeks, and Gernot Rohr, handler of the Super Eagles, confirmed to media on Sunday that the Gent man’s situation is unmanageable. “It is unfortunate that [Moses] Simon won’t be able to make it to the World Cup because of his injury,” Rohr told media. “The test we conducted on him showed that he would need at least three or four weeks more to recover from the injury he is having....

The incredibly rare elephant twins were first spotted in January this year, in the Samburu National Park. Twins form only one percent of all elephant births, meaning the find caused quite a stir among research groups at the time. Conservation charity Save the Elephants has been monitoring the twins ever since. It is incredibly rare for elephant twins to survive in usual circumstances, as mothers do not usually produce enough milk for two calves....

Blues, jazz, and heavy metal bands frequently end up being short-changed by streaming services like Apple, Spotify, and Tidal, says the study. Researchers at Hamburg University and the northern German city’s private Kuehne Logistic University found that mostly pop and hip-hop artists are benefiting from the so-called pro-rata model. In this type of payout, all profits from fees and advertisements are pooled and paid out to the artists on the basis of the share of total tracks....

The National Weather Service (NWS) is warning travel will become “very difficult to impossible,” with around four feet of snow expected for areas south of Buffalo. Drone footage showed snow rolling into Buffalo, with up to four inches accumulating per hour, while a travel ban has now been imposed across the city. In New York’s western Erie County, the town of Orchard Park recorded 5.5 feet on Friday, according to the NWS....

Still, Hedman’s progression over the last year or two has been fun to watch, and given the way he’d played in the Lightning’s first four games … maybe it wasn’t all that dumb, actually. Hedman had seven points and was helping Tampa control play against top competition. In short, he looked the part of a top defenseman. So, Monday’s news — that Hedman will miss 4-6 weeks after surgery on his finger — is something of a disappointment, if only because it effectively guarantees that he’s out of the awards discussion....

Check out the commercial making the case for the move: MORE: When is Super Bowl 2017? Date, location, odds and halftime info for Super Bowl 51 The condiment company created an online petition to go along with the commercial, at www.smunday.org. Heinz says if the petition gets 100,000 signatures, it will send the petition to congress. While some may see this as a joke and a really good marketing campaign, the company appears to really mean business....

“Hot dog wieners come in packs of 10. Hot dog buns come in packs of 8. WHY?!” asked Heinz Ketchup Canada on their online petition. “As the condiment that has been bringing foods together for over 150 years, we’ve decided enough is enough. That’s why we started the Heinz Hot Dog Pact. We’re calling on Big Bun and Big Wiener companies to find the answer to this hot dog packaging mismatch, once and for all....

The goats currently roaming the park are thought to have descended from a herd introduced outside Grand Teton. There are thought to be about 100 goats, but officials are concerned that the population could increase, making their presence in the region irreversible. According to the National Park Service (NPS), “The mountain goat population is currently at a size where complete removal is achievable in a short time, however, the growth rate of this population suggest that complete removal in the near future may become unattainable after a period of about three years....

The values for hemoglobin and hematocrit are reported as part of a complete blood count (CBC) test. Read on to learn what these levels mean and why they are important. What Is Hemoglobin? Hemoglobin is an iron-containing protein that carries oxygen and carbon dioxide. It is located inside the red blood cells. The hemoglobin protein changes its three-dimensional shape in response to changes in the surrounding pH and temperature. In the lungs, hemoglobin binds tightly to oxygen and releases carbon dioxide due to the slightly cooler body temperature and slightly less acidic pH....

According to the club, Coutinho is suffering from a back problem and missed Liverpool’s 3-3 draw at Watford on Saturday as a consequence. Liverpool 10/1 on dabblebet to beat Palace 3-1 The Brazil international has not travelled with the squad for the match at the Rhein-Neckar Arena on Tuesday and submitted a transfer request last week, shortly after Liverpool’s owners Fenway Sports Group announced they will not consider any offers for the 25-year-old....

Southgate has yet to commit himself to a captain to lead his side into World Cup 2018 but was left impressed with the 27-year-old’s display against the Netherlands on Friday. Have taken the armband, he led the Three Lions to a 1-0 win, in which Jesse Lingard got the only goal of the game early in the second half. “He’s got some tremendous human qualities and is a certain leader of men,” the former Aston Villa boss reflected....

After 22 years working under the same manager, the Gunners find themselves in a difficult situation. Wenger may have multiple Premier League titles and FA Cup crowns under his belt, but he is struggling to inspire a side that have now suffered four successive defeats across all competitions and eight losses in their last 13 fixtures. Change is being mooted in north London, despite Wenger’s insistence that he will not be walking away, and club icon Henry is among those being tipped to fill the void and clean up the mess....